The Japanese Ministry of Health, Labor and Welfare (MHLW) will listen to overseas stakeholders\’ opinions from March 14, 2023, on the second and third batches of candidate substances subject to mandatory SDS and labeling requirements under the Industrial Safety and Health Act (ISHL).The two batches of candidate substances include:

• Second batch: 651 substances identified in category 1 of hazard classes other than carcinogenicity, germ cell mutagenicity, reproductive toxicity (CMR) and acute toxicity, to be implemented from April 1st, 2025, and
• Third batch: 818 substances with health hazards in category 2 and below, or chemicals without health hazards but with physical-chemical hazards, to be implemented from April 1st, 2026.